
Stress Urinary Incontinence (SUI)
Stress Urinary Incontinence (SUI) is the involuntary loss of urine
with an increase in abdominal pressure caused by a physical activity
such as coughing, laughing, sneezing, lifting or exercising. Urinary
Incontinence in general is a significant healthcare problem
worldwide; efforts to help sufferers are made difficult by the fact
that it is not seen as being life threatening. Incontinence is
poorly understood, diagnosed and treated by many health care
providers. It is more than twice as prevalent in women as in men and
Stress Urinary Incontinence (SUI) is the most common form. Around 97
percent of SUI patients are female and less than half of the women
suffering from this condition actually seek treatment. The majority
of women suffering in silence are too embarrassed to discuss it with
their doctor, believe it is a normal part of aging and nothing can
be done for it, or fear surgery.
Currently patients have only limited options to cope with this
condition. In most cases pads are used to deal with the symptoms and
pelvic floor muscle training is another non-invasive option to
reduce urinary leakages. In more severe cases surgery is still the
final invasive treatment alternative. There remains a significant
opportunity for new and effective pharmaceutical treatments that
reduce incontinence episode frequency (IEF) and improve women's
quality of life (QoL). Since mid of August 2004 Eli Lilly and
Boehringer Ingelheim got the European Commission approval for
duloxetine for the treatment of women with moderate to severe Stress
Urinary Incontinence (SUI). Duloxetine is the first oral
pharmaceutical to be widely approved that has shown to significantly
reduce the number of urinary leakages and thus improving women´s
quality of life.
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