Our Animal Health business made excellent progress. In 2012, we concluded another successful year with net sales of EUR 1.1 billion and a year-on-year growth of +8.8 percent. This division contributes around 7 percent to our total sales.
Boehringer Ingelheim Animal Health has a wide range of products covering
Modified life vaccine (Lawsonia intracellularis)
For active immunisation of pigs against ileitis due to Lawsonia intracellularis infection.
Enterisol® Ileitis is the first and only vaccine against ileitis. It is licensed to improve weight gain and to reduce growth variability associated with the disease. Enterisol® Ileitis helps to reduce the total antimicrobial use in pork production.
Attenuated live gE-deleted vaccine
Ingelvac® Aujeszky MLV is a gE®-deleted vaccine based on the Bartha K61 strain which is licensed for active immunisation and eradication of Pseudorabies virus in swine production units.
Ingelvac® Aujeszky MLV can be administered both by the intranasal and intramuscular route and creates a well documented humoral and cellular immunity.
Ingelvac® Aujesky MLV is administered intramuscularly and intranasally, depending on the strategy applied.
porcine circovirus type 2, PCV-2
Ingelvac CircoFLEX® is a pig vaccine registered for use as a single vaccination around weaning against the diseases associated with the porcine circovirus type-2 (PCV2). This includes the reduction of disease related clinical signs like mortality, weight loss and lesions in the lymphoid tissue.
Bordetella Bronchiseptica Pasteurella multocida Type D Bacterin-Toxoid
Ingelvac® DART/AR4 are aluminium potassium sulphate based adjuvanted vaccines against progressive atrophic rhinitis (PAR), which consist of a 4-way bacterin-toxoid combination of Bordetella bronchiseptica and Pasteurella multocida type D.
The vaccines provide cross protection against PAR caused by toxigenic Bb and Pm type A and have a very wide safety margin.
Ingelvac® DART/AR4 is administered subcutaneously or intramuscularly.
Inactivated whole cell culture of Mycoplasma hyopneumoniae
Ingelvac® M. hyo is licensed for the active immunisation of pigs against enzootic pneumonia (EP).
It is an efficacious, non-mineral oil-adjuvanted vaccine. Furthermore, it is the first Mycoplasma hyopneumoniae vaccine offering onset of immunity of 2 weeks as well as an improved immune response. Through its advanced depot-system it provides a long lasting and effective protection until slaughter, proven even in high challenge situations.
1-shot vaccine for intramuscular vaccination
Inactivated whole cell culture of Mycoplasma hyopneumoniae
The adjuvant is an aqueous polymer called ImpranFLEX®.
For active immunization of pigs from three weeks of age or older to reduce lung lesions following infection with Mycoplasma hyopneumoniae. Under field conditions, vaccine efficacy has been established by reduction of lung lesions and weight gain improvement.
Onset of protection occurs by two weeks post vaccination and lasts for at least 26 weeks.
Ingelvac MycoFLEX® is administered via a single intramuscular injection (1ml).
Modified live PRRS virus
Ingelvac® PRRS MLV is licensed for the active immunisation against the respiratory and reproductive form of PRRS.
Ingelvac® PRRS MLV, as a truly global vaccine has been proven to offer effective cross protection worldwide (against heterologous EU and US strains) and is also licensed for whole herd mass vaccination.
Ingelvac® PRRS MLV is administered intramuscularly.
For use in non-infectious locomotor disorders to reduce the symptoms of lameness and inflammation. For adjunctive therapy in the treatment of puerperal septicaemia and toxaemia (mastitis-metritis-agalactia syndrome) with appropriate antibiotic therapy. For the relief of post operative pain associated with minor soft tissue surgery such as castration.
Metacam® is a potent Non-Steroidal-Anti-Inflammatory exerting anti-inflammatory, anti-exudative, analgesic and antipyretic properties. Through its long duration of action, Metacam® has demonstrated to relieve pain and control inflammation resulting in sustained restoration of the animal's well being and productivity.
single shot intramuscularly
Penethamate hydriodide; Benetamine-penicillin, Framycetin
For the treatment of subclinical infections present at drying off and assistance in preventing new infections as well as acute clinical mastitis during the dry period in dairy cattle.
Benestermycin® consists of a combination of antibiotics which act synergistically and provide short and long acting broad spectrum efficacy against mastitis causing pathogens of relevance during the entire dry off period.
1 intramammary syringe per quarter
For use in acute respiratory infection with appropriate antibiotic therapy to reduce clinical signs in cattle. For use in diarrhoea in combination with oral re-hydration therapy to reduce clinical signs in calves of over one week of age and young, non-lactating cattle. For adjunctive therapy in the treatment of acute mastitis, in combination with antibiotic therapy.
Metacam® is a potent Non-Steroidal-Anti-Inflammatory exerting anti-inflammatory, anti-exudative, analgesic and antipyretic properties. Through its long duration of action, Metacam® was demonstrated to relieve pain and control inflammation resulting in sustained restoration of the animal’s well being and productivity.
For the treatment of clinical and subclinical mastitis in cattle caused by Gram positive pathogens susceptible to penethamate.
Parenterally administered Mamyzin® crosses the blood milk barrier achieving therapeutic concentrations of penicillin in milk for 24 hours upon injection. The absorption of penethamate is 8 times faster and 10 times higher than that of benzylpenicillin. An injection of Mamyzin® treats all four quarters reducing the workload and eliminating any risk of contamination as a result of administration.
Cefalexin and Kanamycin.
Treatment of clinical mastitis in lactating dairy cows for bacteria susceptible to the combination of cefalexin and kanamycin such as Staphylococcus aureus, Streptococcus dysgalactiae, Streptococcus uberis and Escherichia coli.
For intramammary use.
Treat the infected quarter(s) twice, leaving an interval of 24 hours between treatments. Use the contents of one syringe (containing 200 mg cefalexin as monohydrate and 100,000 I.U. kanamycin as monosulphate) per quarter per treatment. Each syringe is for single use only.
Before infusion, the udder should be milked out completely, the teat should be thoroughly cleaned and disinfected and care should be taken to avoid contamination of the injector nozzle.
Bovikalc® is a nutritional supplement that helps to maintain normal serum calcium level in dairy cows around parturition.
Bovikalc® is developed as a bolus that consists of two calcium sources, calcium chloride and calcium sulphate. When administered, the bolus will disintegrate quickly in the rumen. The calcium chloride will be available immediately, while the calcium sulphate will provide long term release of calcium.
Bovikalc® delivers the following proven benefits:
Bovikalc® is administred using a special bolus gun. Each bolus contains 42 g of calcium.
Diakur® Plus is a nutritional supplement that helps to re-hydrate young calves under stress caused by changes in feed or the environment.
Diakur® Plus is a unique formula containing patented hydrophobic citrus fibre which helps by removing the pathogenic bacteria from the intestinal system. Diakur® Plus supports fast absorption of electrolytes and water, and can be fed with milk, milk replacer or water.
Diakur® Plus delivers the following proven benefits:
Diakur® Plus is a very flexible product. It can be given in milk, milk replacer or water.
Alleviation of inflammation and pain in acute and chronic musculo-skeletal disorders, such as osteoarthritis, in dogs.
Reduction of post-operative pain
Metacam® oral formulations are administered once daily with or without food. The oral suspension can be administered either via a dispenser syringe or dropper.
Metacam® solution for injection is administered as a single dose. It can be administered subcutaneously to cats, and also intravenously to dogs.
For the treatment of congestive heart failure in dogs
As the first of a new class of heart treatments termed Inodilators, Vetmedin® has been shown to significantly improve the clinical signs and extend the life expectancy in dogs with congestive heart failure. Vetmedin® works through two complementary modes of action; it opens up the blood vessels taking blood to and away from the heart, thereby lowering the pressure on the heart and reducing the work the heart has to do to pump blood around the dog's body. At the same time, Vetmedin® has a direct effect on the heart muscle, helping it to beat stronger and pump blood more efficiently.
Canikur® is a very effective and clinically documented "4 in 1" product for support of acute, uncomplicated diarrhoea in dogs.
Canikur® has been formulated to remove pathogenic bacteria from the intestinal system, restore the electrolyte balance, stabilise the intestinal epithelium and normalise faeces consistency.
Canikur® delivers the following benefits:
Canikur® is presented in 4.4g chewable tablets for dogs.
Canikur® Pro is a triple-action paste combination of probiotics for the support of a healthy and balanced gut flora in dogs, particularly in cases of gastro-intestinal disorders characterized by gut imbalance.
Canikur® Pro delivers the following benefits:
Canikur® Pro is filled in two sizes of disposable syringes with 15 ml or 30 ml, respectively. The syringes are labelled and equipped with a dial-a-dose plunger and packed in tamper-proof carton boxes. The tip of the syringe is fitted with a protective cap. Canikur® Pro is easy to use and highly palatable for the dog.
Canosan® is an all-natural nutritional supplement specially formulated to help maintain healthy joint function in dogs and cats.
Canosan® contains Gonex®, which is an extract from the Green lipped mussels. Gonex® is extracted by a unique gentle process and has proven beneficial effects in support of joint health.
Canosan® delivers the following proven benefits:
Canosan® is delivered in blister packed, highly palatable chewable tablets. Canosan® comes in the presentation form of 600 mg tablets for cats and small dogs, 2 g tablets for dogs (>10 kg) and 2% and 4% pellets.
Cardiguard® is a high concentrated omega-3 fatty acid supplement specifically formulated to support of heart health in dogs.
Cardiguard® is made with quality fish oil rich in the essential omega-3 fatty acids Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA), the 2 fatty acids which have been associated with benefits for heart health.
Cardiguard® delivers the following benefits:
Cardiguard® is easy to use and is highly palatable. Cardiguard® is presented in a 43 ml pump-action bottle and delivers 0.2 ml per stroke.
Administration: Two pump strokes per 5 kg bodyweight per day mixed with normal feed.
Seraquin® is an all-natural nutritional supplement specially formulated to help maintain healthy joint function in dogs and cats.
Seraquin® contains Glucosamine HCl, Chondroitin sulphate and Curcumin (a potent antioxidant), a composition that is in line with clinical evidence and recommendations.
Seraquin® delivers the following proven benefits:
Seraquin® is delivered in blister packed, highly palatable chewable tablets. Seraquin® comes in the presentation form of 800 mg tablets for cats and small dogs and 2 g tablets for dogs (>10 kg).
Viacutan® Plus is a high concentrated omega-6 (borage oil) and omega-3 (fish oil) fatty acid supplement formulated to support skin health in dogs and cats.
Viacutan® Plus contains essential fatty acids with natural antioxidants for dogs and cats. Viacutan® Plus improves the condition of the skin and coat and protects from e.g. dry skin, dry coat, hair fall, itching and scratching.
Viacutan® Plus delivers the following benefits:
Viacutan® Plus is packed in unique airtight 95 ml dosers and 550 mg blister capsules. Viacutan® Plus can be given once daily either directly into the dog’s mouth or mixed with food.
Incorporates North American (Kentucky/95) & Eurasian (Newmarket/2/93) EIV A1 & A2 strains
For the active immunisation against Equine Rhinopneumonitis-Influenza Virus infections.
intra-muscular as well as intra-nasal application
The following fungal species are included in the vaccine
Insol® Dermatophyton contains the preservative Thiomersal.
Active immunisation and treatment of horses against dermatophytosis caused by the above mentioned fungi.
Dermatophytosis is the contagious superficial infection of the skin caused by dermatophytes (ringworm or tinea) which is the most common skin disease in horses. The spores can survive for years.
Insol® Dermatophyton contains immunogenic strains of fungus. Based on a special manufacturing process the inactivated microconidia stimulate cell-mediated immune response in particular. Insol® Dermatophyton contains no adjuvants or adsorbents.
For both prophylactic and therapeutic treatment use 2 intra-muscular injections 14 days apart.
Butylscopolaminiumbromide and Metamizole sodium (dipyrone).
For the management of abdominal pain associated with equine colic.
Buscopan® Compositum contains butylscopolaminiumbromide, an antispasmodic agent, and dipyrone, a non-steroidal anti-inflammatory drug (NSAID). Buscopan® Compositum does not mask the symptoms of surgical colic cases and does not produce paralysis of the gut.
Butylscopolaminiumbromide is a quaternary ammonium derivative of scopolamine. Like other belladonna alkaloid derivatives, this compound antagonises the actions of acetylcholine at the muscarinic receptor and also possesses some activity at nicotinic receptors.
Dipyrone shows anti-inflammatory, analgesic and antipyretic effects. Data indicate that the mechanism of action of dipyrone, like other NSAIDs, is probably associated with an inhibitory effect on prostaglandin synthesis. Furthermore, it antagonises the effects of bradykinin and histamine.
single intravenous injection
Oral suspension and solution for injection: For use in the alleviation of inflammation and relief of pain in both acute and chronic musculo-skeletal disorders.
Solution for injection: For the relief of pain associated with equine colic.
Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class (COX-2 selective) which acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory, analgesic, anti-exudative and antipyretic effects. It reduces leukocyte infiltration into the inflamed tissue. To a minor extent it also inhibits collagen-induced thrombocyte aggregation.
The honey flavoured oral suspension is highly palatable and is easy to administer over feed or directly into the mouth. The complimentary dispenser syringe allows an accurate and easy dose adjustment.
Metacam® is also available as an aqueous solution for injection.
The different forms of presentations allow the initiation of therapy with an injection followed by the treatment with the oral suspension which can be administered by the horse owner.
The Metacam® oral suspension can be administered with or without food.
The Metacam® solution for injection is administered as a single intravenous injection.
Sedivet® is indicated for use as a sedative to facilitate handling, examination, treatment and as a premedication agent prior to general anaesthesia.
Sedivet® is a synthetic alpha-2 sympathomimetic agent. As with other agents in this class, there is a dose dependent sedation associated with tolerance of pain.
The sedative effect of Sedivet® is induced by a stimulation of presynaptic alpha-2 receptors in the central nervous system. Sedivet possesses a strong affinity for those receptors. Lowering of the head is the first sign of sedation followed by lethargy, reduced sensitivity to environmental stimuli and immobility. Onset of sedation occurs in one to two minutes and lasts 40 to 80 minutes. Induction of anaesthesia may be initiated 8-10 minutes after administration of Sedivet®.
single intravenous injection
Symptomatic treatment of acute, sub-acute and chronic respiratory disease of the upper and lower respiratory tract, where abnormal mucus of increased viscosity is present and where secretolysis is necessary or desirable.
Sputolysin® alters the constituents and viscosity of abnormal respiratory mucus and improves the efficiency of the respiratory tract clearance mechanism. A secondary antitussive action has also been demonstrated. The effect on mucus can change the character and frequency of a cough and alter the consistency and quantity of nasal discharges. Therefore, in some cases, there will be an initial increase in visible nasal discharges and/or frequency of cough prior to clinical improvement.
powder for oral administration
Treatment of acute and chronic respiratory disease where airway obstruction due to bronchospasm and/or mucus accumulation is a contributing factor and improved mucociliary clearance is desirable
To be used alone or as adjunctive therapy in Chronic Obstructive Pulmonary Disease (COPD)
Acute, sub-acute and chronic respiratory allergic conditions
Ventipulmin® provides effective and sustained control of allergic non-infectious respiratory disorders.
Ventipulmin® is also an adjunctive therapy in combination with antibiotics for the treatment of infectious respiratory disorders as it leads to peak performance in respiratory function and working.
powder for oral administration
The innovative and long-lasting insect repellent for both horse and rider.
Centaura® is registered for use on horses and humans and its efficacy has been proven in numerous studies in a wide range of climates and against all common insect species.
Centaura® delivers the following proven benefits:
Centaura® comes in a 250 ml spray. Centaura® is easy to apply with the unique Airosol and environmentally friendly spray system that uses air, rather than flammable or hazardous propellants.
Equitop® Gonex is a feed supplement to support and maintain mobility and healthy joints in horses.
Equitop® Gonex contains GLME (Green Lipped Mussel Extract) from the Perna canaliculus as the active ingredient, also the key ingredient in Canosan®. Equitop® Gonex can be used long term on its own or together with medicinal products such as Metacam® horse.
Equitop® Gonex delivers the following proven benefits:
Equitop® Gonex is a sugar-coated pearl granulate for oral administration. The presentation form is 750 g. One measure spoon contains 25 g pearl granules.
Equitop® Myoplast is a high-quality amino acid feed supplement for the support of muscle build up and functions in the horse.
Equitop® Myoplast is a unique combination of 18 amino acids, derived from blue-green algae. Equitop® Myoplast is recommended for use in periods of intensive training and competition, for training at the beginning of the season, for young horses in training, for older horses with increased need for protein, for brood mares, after injuries and during rehabilitation.
Equitop® Myoplast delivers the following proven benefits:
Equitop® Myoplast is a sugar-coated pearl granulate for oral administration. The presentation form is 1.5 kg.
Equitop® Pronutrin is a dietetic complementary feed for the reduction of stress reactions in horses.
Equitop® Pronutrin contains 77% Apolectol, a unique combination of fruit and vegetable fibres, glycerol and lecithin. The properties of the various ingredients in Equitop® Pronutrin provide nutritional support for horses with symptoms of gastric stress reactions such as poor appetite, poor performance (e.g. sport horses), loss of appetite, loss of weight, general depression, bruxism, colic, increased salivation and cribbing.
Equitop® Pronutrin delivers the following proven benefits:
Equitop® Pronutrin comes in the presentation form of 3.5 kg.