Value through Innovation27 April 2015

Cardiovascular diseases remain the leading cause of premature death in the developed world.

Acute Myocardial Infarction (AMI) is still the main cause of death in the industrial nations, with around three million people suffering from it every year. During the last decade, the treatment of patients with AMI has been revolutionised.

Time is an important factor for successful treatment

The most important factor for a successful treatment of an acute myocardial infarction is time to treatment. Reality shows, however, that from onset of symptoms until treatment a lot of precious time is wasted. Delays are caused by the patient's hesitance to call for help as well as by ambulance response and journey times and slow in-hospital procedures. Thrombolytic therapy has established itself as one of the most successful modern treatment options of an acute myocardial infarction. It is easy to apply, is available in all hospitals and is considered safe in view of the serious nature of the disease.


Actilyse® (alteplase)

  • Fibrinolytic treatment of acute myocardial infarction
  • Thrombolytic treatment of acute massive pulmonary embolism
  • Catheter clearance due to thrombotic occlusion

Actilyse® is also registered for the indication acute ischaemic stroke.

Metalyse® (tenecteplase)

  • Fibrinolytic treatment in acute myocardial infarction


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