AIDS is a continuously growing pandemic, with 40 million people infected with the human immunodeficiency virus (HIV). It is no longer a disease predominantly affecting men. Since 1985, the percentage of women among adults living with HIV has grown particularly, from 35 % to48 % globally. Worldwide, there are now nearly 18 million women living with the disease. As women may respond to HIV/AIDS treatment differently than men, there is a need for additional medical investigation.
We are committed to improving HIV therapy by providing physicians and patients with innovative antiretroviral drugs. The BoehringerIngelheim Corporate HIV/AIDS website
Viramune® (nevirapine)
A non-nucleoside reverse transcriptase inhibitor (NNRTI), indicated for use in combination with other antiretroviral agents for the treatmentof HIV-1 infection. Resistant virus emerges rapidly and uniformly when
Viramune® is administered as monotherapy. Therefore,
Viramune® should always be administered in combination with at least two additional antiretroviral agents.
Viramune® may be used alone as a single oral dose to the mother during labour and a single oral dose to the infant within 24 hours after birth for the prevention of mother-to-child transmission of HIV-1 pregnant women who are not taking antiretroviral therapy at time of labour.
Aptivus® (tipranavir)
A non-peptidic protease inhibitor blocks the viral protease, an enzyme needed to complete HIV replication.
Aptivus®, co-administered with low dose ritonavir, is indicated for combination antiretroviral treatment of HIV-1 infection in highly pre-treated adult patients with virus resistant to multiple protease inhibitors. This indication is based on the results of two phase III studies, performed in highly pre-treated patients (median number of 12 prior antiretroviral agents) with virus resistant to protease inhibitors (see details of resistance profile of patients' HIV at baseline in section 5.1 of the Summary of Product Characteristics). In deciding to initiate treatment with Aptivus®, co-administered with low dose ritonavir, careful consideration should be given to the treatment history of the individual patient and the patterns of mutations associated with different agents. Genotypic or phenotypic testing (when available) and treatment history should give the use of Aptivus®."
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